Infanrix is a 3 in 1 shot (diphtheria, tetanus, acellular pertussis vaccine) given to infants and children 6 weeks through 6 years of age. (see GlaxoSmithKline product insert for recommended schedule and other indications).
- Vaccine ingredients: Aluminum hydroxide, sodium chloride, polysorbate 80 (Tween 80), formaldehyde, modified Stainer-Scholte liquid medium, glutaraldehyde, fenton medium containing a bovine extract, modified Latham medium derived from bovine casein.
- Estimated Efficacy: Efficacy of diphtheria toxoid in Infanrix was based on immunogenicity (blood immune response) and was tested in only 45 infants one month following the completion of three doses of Infanrix vaccine. At this time, 100 percent of infants had a blood immune response to Infanrix
- Use with Other Vaccines: In clinical trials, Infanrix was given with HIB, pneumococcal, hepatitis B, inactivated polio or MMR vaccines. There is no information in the package insert about the safety or effectiveness of giving Infanrix simultaneously with inactivated or live influenza, rotavirus, varicella or hepatitis A vaccines.
Animal reproduction studies have not been conducted with Infanrix. It is also not known whether Infanrix can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Infanrix has not been evaluated for carcinogenic or mutagenic potential, or for impairment of fertility.
