National Vaccine Information Center

Diphtheria and Tetanus Toxoids Adsorbed

Published: April 6, 2024

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Diphtheria and Tetanus Toxoids Adsorbed   (diphtheria and tetanus toxoid vaccine manufactured by Sanofi Pasteur.) (Discontinued by the manufacturer in 2023)  

  • Frequently Reported Adverse Events: In pre-licensure clinical trials, pain, redness, and swelling at the injection site, loss of appetite, crying, and fever. Adverse events were monitored for only 24 hours following vaccination.
  • Serious Reported Adverse Events:  After licensure (post marketing) adverse event reports have included injection site pain, swelling and hypersensitivity; syncope; convulsion; somnolence; headache; rash; pallor; itching; lymphadenopathy.

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