National Vaccine Information Center

Daptacel

Published: April 6, 2024

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Daptacel   is a 3 in 1 shot (diphtheria, tetanus, acellular pertussis vaccines) given to children under age seven (see Sanofi Pasteur product insert for recommended schedule and other indications).

  • Vaccine ingredients: Aluminum phosphate, formaldehyde, ammonium sulfate, modified Mueller-Miller casamino acid medium without beef heart infusion, glutaraldehyde, 2-phenoxyethanol, Stainer-Scholte medium, casamino acids, dimethyl-beta-cyclodextrin, Mueller’s growth medium.
  • Use with Other Vaccines:In clinical trials, DAPTACEL was given with HIB, inactivated polio (IPV), hepatitis B, pneumococcal, and MMR or varicella vaccines. There is no information in the product insert about the safety or effectiveness of giving DAPTACEL simultaneously with inactivated or live influenza, rotavirus, or hepatitis A vaccines. DAPTACEL has been noted to reduce meningococcal antibody responses to Menactra when administered one month after Menactra. In cases where DAPTACEL and Menactra are to be administered, the vaccines were recommended to be given at the same time or else one month apart, with Menactra administered first.

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