CAPVAXIVE is a 21-valent pneumococcal conjugate vaccine (PCV) manufactured by Merck Sharp & Dohme Corp. containing S. pneumonia serotypes 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 15B (deOAc 15B), 16F, 17F, 19A, 20A,22F, 23A, 23B, 24F, 31, 33F, and 35B individually conjugated to CRM197. Each pneumococcal capsular polysaccharide is active and individually conjugated to CRM197 carrier protein. Each 0.5mL dose contains 4mcg of each Streptococcus pneumoniae polysaccharide serotype present within the vaccine conjugated to about 65mcg of CRM197 carrier protein, 0.50mg of polysorbate 20, 4.49mg sodium chloride, 1.55mg L-histidine, and water for injection. CAPVAXIVE does not contain any preservatives.
