National Vaccine Information Center

Possible Adverse Events after Diphtheria Vaccination

Published: July 19, 2024

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According to the CDC, possible side effects from DTaP vaccine include: 

  • Pain, swelling, and redness at the injection site
  • Fatigue
  • Fussiness
  • Fever
  • Loss of appetite
  • Vomiting
  • Non-stop crying for 3 hours or longer
  • Fever greater than 105 F
  • Swelling of the entire vaccinated limb
  • Severe allergic reaction
  • death

According to the CDC, possible side effects from Tdap vaccine include: 

  • Pain, redness, and swelling at the injection site
  • Ringing in the ears
  • Headache
  • Nausea, diarrhea, stomach ache, vomiting
  • Joint pain
  • Fatigue
  • Fever
  • Dizziness or fainting
  • Severe allergic reaction
  • Death

According to the CDC, possible side effects from Td vaccine include: 

  • Pain, redness, and swelling at the injection site
  • Fever
  • Fatigue
  • Headache
  • Nausea and vomiting
  • Stomachache
  • Ringing in the ears
  • Vision changes
  • Dizziness or fainting
  • Severe allergic reaction
  • Death

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