TDVAX is a 2 in 1 shot (tetanus and diphtheria) for persons over the age of seven (see MassBiologics product insert for recommended schedule and other indications).
- Vaccine Ingredients: Thimerosal, aluminum phosphate, formaldehyde, modified Mueller’s media which contains bovine extracts.
- Estimated Efficacy: Efficacy of diphtheria toxoid in TDVAX was based on immunogenicity (blood immune response) of six vaccine recipients tested after three doses of TDVAX were given as a primary series. All vaccine recipients were noted to have blood antibody levels considered protective against diphtheria. When administered as a booster dose, all 140 adolescent male vaccine recipients tested were noted to have blood antibody levels believed to be protective against diphtheria.
- Use with Other Vaccines: No clinical trials examined the safety or effectiveness of administering the vaccine with any other U.S. licensed vaccine.
Animal reproduction studies have not been conducted with TDVAX. It is not known whether TDVAX can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. TDVAX has not been evaluated for carcinogenic or mutagenic potential, or for impairment of fertility.
