On June 11, 2010, the CDC issued revised recommendations and added severe combined immunodeficiency (SCID) as a contraindication to receiving rotavirus vaccines. SCID is a group of rare disorders caused by mutations in various genes involved in the function and development of T- and B- lymphocytes. The addition of this contraindication occurred following reports of vaccine-acquired rotavirus infections and prolonged vaccine-strain shedding within this specific population.
The CDC updated its rotavirus vaccine recommendations in October 2011 and added a prior history of intussusception as a contraindication of rotavirus vaccines. In this updated recommendation, the CDC reported that infants with a history of intussusception are at a higher risk for a repeated case; however, no data was available to determine the risk of a subsequent case of intussusception after rotavirus vaccination in infants with a prior history of intussusception. Intussusception between day one and day 21 following the first and second dose of rotavirus vaccine was recognized as a vaccine injury and added to the National Vaccine Injury Compensation Program’s Vaccine Injury Table on July 23, 2015.
In 2018, the CDC reported that only 73.2 (71.6–74.7) percent of children between 19 and 35 months of age had received the rotavirus vaccine series in 2017. Currently only Idaho, Louisiana, North Dakota, Ohio, Pennsylvania, Rhode Island, Virginia, West Virginia, and Wyoming require rotavirus vaccination for childcare enrollment; however, exemptions may be available. More information on vaccine exemptions for school and childcare can be found on our NVIC State Law & Vaccine Requirements Page
IMPORTANT NOTE: NVIC encourages you to become fully informed about rotavirus and rotavirus vaccines by reading all sections in the Table of Contents, which contain many links and resources such as the manufacturer product information inserts, and to speak with one or more trusted health care professionals before making a vaccination decision for yourself or your child. This information is for educational purposes only and is not intended as medical advice.
